lysyl oxidase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T39986	LOX-IN-3 dihydrochloride		Lipoxygenase
	LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX). LOX-IN-3 dihydrochloride inhibited bovine LOX (IC50<10 μM) and human LOXL2 (IC50<1 μM)activities.		Lipoxygenase
T13475	β-Aminopropionitrile	3-Aminopropionitrile,BAPN	Others , Endogenous Metabolite
	β-Aminopropionitrile (3-Aminopropionitrile) is a selective inhibitor of lysyl oxidase.		Others , Endogenous Metabolite
T12584	PXS-5120A		Others , Monoamine Oxidase
	PXS-5120A is an irreversible fluoroallylamine Lysyl Oxidase-like 2/3 (LOXL2/3) inhibitor with anti-fibrotic activity.		Others , Monoamine Oxidase
T12585	PXS-5153A		Others , Monoamine Oxidase
	PXS-5153A is an effective, selective, and fast-acting inhibitor of lysyl oxidase like 2/3 enzymes with enzymatic activity almost entirely blocked within 15 minutes. PXS-5153A could reduce crosslinks and ameliorates fibro...		Others , Monoamine Oxidase
T26969	CCT365623	CCT-365623,CCT 365623	Monoamine Oxidase
	CCT365623 is an orally bioavailable Lysyl Oxidase inhibitor with good anti-LOX potency, selectivity, pharmacokinetic properties, as well as anti-metastatic efficacy.		Monoamine Oxidase
T69913	Lenumlostat	PAT-1251,GB2064	Monoamine Oxidase
	Lenumlostat is an orally available, selective and potent lysyl oxidase-like protein 2 (LOXL2) inhibitor with inhibitory effects on hLOXL2, hLOXL3 and LOXL2 for the study of fibrotic diseases.		Monoamine Oxidase
T20533	NNK	Nicotine-derived nitrosamine ketone	Lipoxygenase
	NNK (Nicotine-derived nitrosamine ketone) is a procarcinogen and a major tobacco-specific toxicant. It inhibits the expression of lysyl oxidase which is a tumor suppressor.		Lipoxygenase
T76700	Simtuzumab	GS 6624,AB 0024	Monoamine Oxidase
	Simtuzumab is a monoclonal antibody against lysyl oxidase-like protein 2 (LOXL2). Simtuzumab can be used to treat primary sclerosing cholangitis (PSC) and is not effective in patients with bridging fibrosis or compensato...		Monoamine Oxidase
T20852	Triamcinolone diacetate
	Triamcinolone diacetate is an antagonist of Lysyl oxidase.
T38294	4-Deoxypyridoxine hydrochloride		S1P Receptor
	4-Deoxypyridoxine (4-DPD) is a vitamin B6 antimetabolite with diverse biological activities. It inhibits transport of pyridoxine , pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells. 4-DPD inhib...		S1P Receptor
T38006	LOX-IN-3
	LOX-IN-3, an orally active inhibitor of lysyl oxidase (LOX), holds potential application in the fields of fibrosis, cancer, and angiogenesis research[1].
T60296	PXS-4787
	PXS-4787 is a potent and selective inhibitor of lysyl oxidase (LOX) with broad-spectrum activity. It effectively suppresses lysyl oxidase activity by acting on its mechanisms. The compound displays inhibitory effects wit...
T10719	CCT365623 hydrochloride		Lipoxygenase
	CCT365623 hydrochloride is an orally active inhibitor of lysyl oxidase (LOX) (IC50: 0.89 μM). It suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF.		Lipoxygenase
T12371	PAT-1251 Hydrochloride		Others
	PAT-1251 Hydrochloride is a potent, selective and oral inhibitor of lysyl oxidase-like 2 (LOXL2)(hLOXL2 and hLOXL3 with IC50s of 0.71 and 1.17 μM , respectively),		Others
T61479	LOX-IN-3 dihydrochloride monohydrate
	LOX-IN-3 dihydrochloride monohydrate (Compound 33) is a lysyl oxidase (LOX) inhibitor with oral activity. It is specifically designed for research purposes in the areas of fibrosis, cancer, and angiogenesis [1].
T72103	β-Aminopropionitrile hydrochloride	BAPN hydrochloride
	β-Aminopropionitrile (BAPN) hydrochloride is a specific, irreversible, and orally active inhibitor of lysyl oxidase (LOX), effectively targeting the active site of LOX or LOXL isoenzymes.
T12585L	PXS-5153A monohydrochloride	PXS-5153A monohydrochloride (2125956-82-1 free base)	Others
	PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC 50 of <40 nM for LOXL2 across all mammalian species and an IC 50 of 6...		Others
T60438	PXS-6302
	PXS-6302 is an irreversible inhibitor of lysyl oxidase with IC50s of 3.7 μM for Bovine LOX, 3.4 μM for rh LOXL1, 0.4 μM for rh LOXL2, 1.5 μM for rh LOXL3, 0.3 μM for rh LOXL4, respectively. PXS-6302 can readily penetrate...